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Please might you introduce yourselves and description your roles at OLS?
YG: My identify is Yael Geva, and I’m the Head of Operations at IDEA-Bio Ltd in Tel Aviv, Israel.
AF: I’m Andreas Friese, and I’m the Head of Gross sales and COO at OLS OMNI Life Science (OLS).
Screening of stay Zebrafish in multiwell plates with Hermes imaging system by IDEA Bio. Picture Credit score: IDEA Bio-Medical
What business does OLS focus on, and the way did the partnership with IDEA Bio-Medical come to life?
AF: OLS’ fundamental space of focus is cell analysis, and we’re striving to be the chosen companion for our prospects in cell analysis. OLS is predicated in Bremen, Germany, and is a family-owned firm. Although OLS has existed in some kind since 2004, the previous few years have allowed OLS to carve out our area of interest in cell analysis.
At OLS, we manufacture our personal merchandise and instrumentation, such because the CASY Cell Counter & Analyzer, which is globally distributed, in addition to the CERO 3D Incubator & Bioreactor, which can also be manufactured in-house and distributed globally. At present, we work intently with IDEA Bio-Medical to seek out corporations throughout the discipline which can be eager and capable of picture what we tradition in our CERO.
How are OLS’ merchandise cultured?
AF: At OLS, we tradition our merchandise in-house all the best way from cells into spheroids, and organoids. OLS cultures stem cells, and even tissue items. Our groups consider that the Hermes WiScan system is an extremely revolutionary, quick device that facilitates the following technology of excessive content material imaging available in the market.
Multiscale of biology lined with Hermes imaging system: from 2D cell tradition to 3D spheroids and entire organisms. Picture Credit score: IDEA Bio-Medical
What’s the focus of IDEA Bio-Medical, and the way does this align with the ethos and focus of OLS?
YG: IDEA Bio-Medical is an Israeli firm. We focus on automated imaging and automatic evaluation for the cell biology discipline. We launched our flagship product, the Hermes WiScan, about ten years in the past. Our market is primarily researchers doing cell biology inside academia and drug discovery pharma corporations doing compound screening in addition to biotech corporations.
There’s a sturdy ideological hyperlink and ethos shared between IDEA Bio and OLS. That is partly attributable to OLS’ innovation: the corporate shouldn’t be solely shopping for and promoting; as an alternative, it’s creating and manufacturing its personal merchandise. The 2 organizations additionally work in complementary areas: OLS is concentrated on the life sciences inside cell biology overlaying pattern preparation and culturing, and right here at IDEA Bio-Medical, we complement that by overlaying imaging and evaluation. Collectively, our two organizations create a whole workflow that may present a pillar of help for the market.
What’s the Hermes imaging system?
YG: The Hermes imaging system is actually a platform for the researcher – or anybody who’s doing life science analysis and desires to visualise and quantitate no matter is going on throughout the cells, on the mobile stage.
The system is able to scanning multiwell plates and slides in a number of fluorescence channels and brilliant discipline channels. It then mechanically analyzes all these photographs and extracts quantitative, significant data from these samples. This may be utilized to a variety of functions, together with most cancers analysis, virology, and immunology – primarily, the system helps something associated to the sphere of cell biology.
CERO 3D cell tradition incubator by OLS OMNI life science. Picture Credit score: OLS OMNI Life Science
What are the options of the Hermes imaging system?
YG: We’re notably enthusiastic about a number of new options within the Hermes imaging system that we’ve lately launched. One of many new options is within the zebrafish space and supplies a full resolution for zebrafish screening in a high-content, automated vogue, overlaying the picture acquisition in addition to the evaluation.
The evaluation is exclusive in that it’s a deep-learning AI-based evaluation that discretely segments all of the compartments throughout the fish, together with the fish define, in a brilliant discipline, non-labeled method. This evaluation encompasses a broad vary of analysis when analyzing zebrafish, which is now an rising mannequin for cell biology.
One other thrilling characteristic is our new automated oil immersion module. Primarily, it permits for fully-automated screening of multiwell plates with oil immersion with none want for person intervention. There is no such thing as a longer any have to manually work with the oil, however the person nonetheless advantages from the excessive decision and the brighter distinction with decrease, shorter time gaps.
Primarily, the system will increase the throughput with out requiring the person to do something; the method is undertaken mechanically. Terabytes of knowledge are being acquired, analyzed, quantified, and documented mechanically – all of the person must do is load the samples into the system to start the method. The opposite profit is that every one the information is analyzed in a non-biased method, which is significant when doing scientific analysis. Reasonably than a human endeavor the segmentation, the system provides the person the actual image of what’s going on of their pattern.
How will the mixed experience of each organizations be used to learn the purchasers of each OLS and IDEA Bio?
AF: Primarily, all the numerous analysis that IDEA Bio has accomplished over the previous few years to develop this AI-driven instrumentation for high-content screening within the zebrafish will now be used for the purchasers from OLS Omni Life Sciences within the areas of cell analysis, cell biology, and 3D cell tradition to carry out correct top-of-the-range evaluation on 3D buildings.
In different phrases, it is a perfect marriage between the 2 organizations: OLS Omni Life Science who develops the tradition methods for a lot of of those cell buildings, and these will then be analyzed precisely and quickly by the instrumentation from IDEA Bio-Medical.
Concerning the audio system
Yael Enzer Geva
Head of Operations at IDEA Bio-Medical
Yael is a biotechnology engineer and has been a part of IDEA Bio-Medical workforce since 2015. Yael has huge expertise supporting gross sales and advertising of scientific lab gear, automated microscopy and picture evaluation software program platforms.
Dr. Andreas Fries
COO at OLS OMNI life sciences
Andreas holds a PHD in life sciences and is the COO of OLS Omni Life sciences since 2018. Andreas has in depth expertise of over a decay within the life science business, main gross sales groups of cell analysis gear and cell tradition units.
About IDEA Bio-Medical Ltd.
IDEA Bio-Medical is based in 2007 via a partnership between YEDA (the Weizmann Institute’s commercialization arm) and IDEA Machine Growth (an innovation hub).
We focus on automated imaging methods and picture evaluation software program, providing a broad vary of organic functions based mostly on the corporate’s distinctive algorithms library. The corporate is creating novel image-based screening platforms for the pharmaceutical business and medical facilities, devoted to broadening the scope of customized medication.
Our WiScan Hermes system incorporates probably the most superior applied sciences at the moment accessible within the machine imaginative and prescient discipline, built-in with engineering methodologies of excessive reliability and high quality on the stage of semi-conductors and digital printing industries, that are the specialty of our mom firm, IDEA Machine Growth Design and Manufacturing Ltd.
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